From: Beneficial effects of ROCEN (Topical Nano-arthrocen) on atopic dermatitis in mice
Behavior type | Date | Oxa | Sham | Rocen + Oxa | Beta + Oxa |
---|---|---|---|---|---|
No. of scratching (per 20 min) | 7th day | 42.8 ± 6.8C | 9.6 ± 3.8 | 14 ± 4.3b | 18 ± 0.3a |
14th day | 18.2 ± 4.1B | 9 ± 4.5 | 10.5 ± 3.5a | 13 ± 3.2 | |
28th day | 108 ± 16.1D | 7.5 ± 1 | 29.6 ± 6.1d | 54.25 ± 18.5b | |
35th day | 113.6 ± 14D | 10 ± 3 | 32.6 ± 10.3d | 50.7 ± 15.3c | |
No. of grooming (per 20 min) | 7th day | 29.8 ± 8.8A | 9.6 ± 3.8 | 8.2 ± 3.9b1 | 16.3 ± 2.1a |
14th day | 21.2 ± 1.9A | 14 ± 1.8 | 18.4 ± 2.7 | 18 ± 1.4 | |
28th day | 67.4 ± 6.5D | 6 ± 7 | 10.5 ± 1.9d1 | 30.5 ± 2.7d | |
35th day | 78 ± 12.5D | 12.5 ± 2.5 | 53.6 ± 10.3a | 39.7 ± 8.2b | |
Time of licking (s) (per 20 min) | 7th day | 341.8 ± 7D | 74 ± 12.1 | 115 ± 41.3d2 | 229.4 ± 71.3 |
14th day | 174 ± 29.5 | 107 ± 48.6 | 129.6 ± 25.1 | 214.3 ± 131 | |
28th day | 294.6 ± 39.2D | 34.3 ± 4.5 | 40.3 ± 1.9d3 | 234.2 ± 19.5a | |
35th day | 340 ± 40.4D | 12.5 ± 2.5 | 58.1 ± 22.3c2 | 229.5 ± 8.5 |