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Table 2 Information about potential antidepressant targets from Epimedium

From: Molecular mechanism of Epicedium treatment for depression based on network pharmacology and molecular docking technology

serial number

name

degree

serial number

name

degree

1

AKT1

41

27

OPRM1

15

2

IL6

38

28

IGF2

14

3

VEGFA

34

29

ADRB2

14

4

EGF

31

30

DRD2

13

5

IL1B

29

31

IRF1

13

6

CCL2

29

32

COL1A1

13

7

MMP9

29

33

SLC6A4

13

8

PTGS2

28

34

GJA1

13

9

SERPINE1

25

35

PLAT

12

10

MMP2

25

36

HTR3A

12

11

PPARG

25

37

DPP4

12

12

CCND1

24

38

PRKCB

11

13

APP

24

39

ADRA2A

11

14

ICAM1

23

40

DRD5

11

15

ESR1

22

41

DRD1

11

16

IL4

21

42

SLC6A3

9

17

HMOX1

21

43

ESR2

9

18

HIF1A

20

44

ADRB1

9

19

IL2

20

45

SLC6A2

9

20

CRP

20

46

MAOB

9

21

STAT1

19

47

GRIA2

7

22

NOS2

18

48

CHRM2

7

23

IL1A

17

49

PON1

7

24

SOD1

17

50

PPP3CA

5

25

AR

16

51

RASA1

4

26

GSK3B

15

52

NR3C2

4