Anti-allergic activities of Umbelliferone against histamine- and Picryl chloride-induced ear edema by targeting Nrf2/iNOS signaling in mice

Table 3 The docking interaction of the UMB with various protein targets

Proteins	PDB ID	RMSD (Å)	H-bonds amino acids	H-bonds numbers	Binding energies (kcal\mol)
TNF-α	2az5	0.319	Gly121, Tyr151	2	−6.9
IL-1β	1itb	0.289	Asn204, Gln236, Asn299	3	−7.3
IL-6	1p9m	1.21			−6.3
iNOS	1dd7	0.308	Lys248, Gly307, Gln304, Arg252	4	−6.8
Nrf2	2flu	0.230	Gly367, Val606, Ala666	3	−6.7
IgE	4grg	0.254	Asn468	1	−6.8

ISSN: 2662-7671