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Fig. 5 | BMC Complementary Medicine and Therapies

Fig. 5

From: Bupi Yishen formula attenuates kidney injury in 5/6 nephrectomized rats via the tryptophan-kynurenic acid-aryl hydrocarbon receptor pathway

Fig. 5

Tryptophan-KA-AhR pathway. BYF increased the production of kynurenic acid and melatonin, whereas it decreased the production of indole-3-acetic acid. The intensities of tryptophan (A), kynurenic acid (B), indole-3-acetic acid (C), and melatonin (D) were measured by LC-MS/MS. (E-F) BYF inhibited the expression of the AhR signaling pathway. n = 3 per group (*P < 0.05, **P < 0.001)

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