Skip to main content
Fig. 1 | BMC Complementary Medicine and Therapies

Fig. 1

From: Evaluation of cholinesterase inhibitory and antioxidant activity of Wedelia chinensis and isolation of apigenin as an active compound

Fig. 1

Cholinesterase inhibitory activities of the extract and fractions of W. chinensis. (A) Inhibition of acetylcholinesterase (AChE) by extract and fractions of W. chinensis and standard donepezil. IC50 (μg/ml): CME, 93.64 ± 0.28; PEF, 152.60 ± 1.14; CLF, 121.97 ± 0.74; EAF, 57.76 ± 0.37; AQF, 40.02 ± 0.16; DON, 9.21 ± 0.45. (B) Inhibition of butyrylcholinesterase (BChE) by extract and fractions of W. chinensis and standard galantamine. IC50 (μg/ml): CME, 69.09 ± 0.44; PEF, 148.87 ± 0.50; CLF, 122.50 ± 0.20; EAF, 48.41 ± 0.05; AQF, 31.79 ± 0.18; GAL, 10.62 ± 0.19. Results are expressed as mean ± SD (n = 3). Means with different letters (a-f) differ significantly (P < 0.05). CME, crude methanolic extract; PEF, petroleum ether fraction; CLF, chloroform fraction; EAF, ethylacetate fraction; AQF, aqueous fraction; DON, Donepezil; GAL, Galantamine

Back to article page