Phytochemical, acute toxicity and renal protective appraisal of Ajuga parviflora hydromethanolic leaf extract against CCl4 induced renal injury in rats

Table 8 Effect of APHM on renal histoarchitecture after CCl₄ induced renal injury in rats

Treatment Groups	Doses (mg/kg)	Tubular congestion	Tubular cast	Glomerular congestion	Blood vessel congestion	Inflammatory cells	Epithelial Desquamation
Naïve	–	–	–	–	–	–	–
Control	–	+++	+++	+++	++	+++	+++
APHM^a	100	++	+	++	+	+	++
APHM	200	+	+	+	+	–	+
APHM	300	+	–	–	–	–	–
Silymarin	100	++	+	++	–	+	+

Naïve groups did not received any treatment while control received CCl₄ only
n = 6,
(+) low (++) moderate (+++) severe presence of histological abnormality while (−) indicates absence of histological abnormalities
^aAjuga parviflora hydromethanolic extract

ISSN: 2662-7671