Table 7 Effect of GABAA antagonist bicuculline on the analgesic response of samples
From: Evaluation of antinociceptive activity of Ilex dipyrena Wall. in mice
Treatment Dose | Without Bicuculline | With Bicuculline | |||
|---|---|---|---|---|---|
Writhing count | Inhibition (%) | Writhing count | Inhibition (%) | ||
Control (2% Tween 80) | 66.19 ± 1.71 | – | 64.44 ± 1.83 | – | |
Crd-Id | 100 | 24.29 ± 2.15* | 63.29 | 47.23 ± 2.11ns | 26.70 |
Crd-Id | 200 | 22.28 ± 2.71** | 66.33 | 43.87 ± 1.66* | 31.92 |
Chl-Id | 75 | 21.11 ± 3.19** | 68.14 | 42.22 ± 0.98* | 34.48 |
Et-Id | 75 | 25.57 ± 2.18** | 61.36 | 49.39 ± 1.78ns | 23.35 |
Fr.Chl-Id 46 | 75 | 20.48 ± 1.78*** | 69.03 | 48.48 ± 2.01ns | 24.76 |
Fr.Chl-Id 47 | 75 | 21.63 ± 2.12** | 67.31 | 47.31 ± 1.77ns | 26.58 |
Fr.Chl-Id 48 | 75 | 19.73 ± 1.06*** | 70.19 | 41.19 ± 1.91* | 36.08 |