Table 4 subgroup analysis
Variables | Subgroup analysis based on | Number of trials | Mean difference (95%CI) | Within study heterogeneity | Between study heterogeneity | |
|---|---|---|---|---|---|---|
TG | Participants condition | Type 2 diabetes | 5 | −22.46 (−40.27, −4.65) | 0% | 0.001 |
Other condition | 4 | −40.86 (−93.61, 11.88) | 97% | |||
Amount of apple vinegar | > 15 mL/day | 5 | − 47.59 (−101.58, 6.67) | 96% | < 0.001 | |
≤ 15 mL/day | 4 | −21.91 (−35.23, −8.60) | 0% | |||
Duration | >  8 weeks | 4 | −48.22 (−92.83, − 3.60) | 96% | < 0.001 | |
≤ 8 weeks | 5 | −9.51 (− 33.63, 14.60) | 32% | |||
TC | Participants condition | Type 2 diabetes | 5 | −11.51 (− 18.16, −4.86) | 0% | 0.01 |
Other condition | 4 | −3.21 (−8.81, 2.40) | 47% | |||
Amount of apple vinegar | > 15 mL/day | 5 | −4.00 (−10.19, 2.19) | 46% | 0.03 | |
≤ 15 mL/day | 4 | −10.22 (− 16.46, −3.98) | 0% | |||
Duration | >  8 weeks | 4 | −7.61 (−14.29, −0.94) | 49% | 0.75 | |
≤ 8 weeks | 5 | −5.71 (−14.33, 2.92) | 49% | |||
LDL-C | Participants condition | Type 2 diabetes | 5 | −5.39 (− 14.31, 3.53) | 48% | 0.002 |
Other condition | 4 | 1.62 (−9.85, 5.85) | 87% | |||
Amount of apple vinegar | > 15 mL/day | 5 | −0.59 (−11.73, 10.55) | 85% | 0.003 | |
≤ 15 mL/day | 4 | −4.34 (−12.51, 3.84) | 38% | |||
Duration | >  8 weeks | 4 | −1.41 (− 16.36, 13.55) | 90% | 0.02 | |
≤ 8 weeks | 5 | −1.66 (−8.83, 5.51) | 38% | |||
HDL-C | Participants condition | Type 2 diabetes | 5 | 0.21 (−2.17, 2.60) | 34% | 0.10 |
Other condition | 4 | 1.73 (0.28, 3.18) | 0% | |||
Amount of apple vinegar | > 15 mL/day | 5 | 0.39 (−1.78, 2.57) | 56% | 0.49 | |
≤ 15 mL/day | 4 | 1.61 (−0.52, 3.75) | 0% | |||
Duration | >  8 weeks | 4 | 1.62 (− 0.07, 3.30) | 0% | 0.32 | |
≤ 8 weeks | 5 | 0.52 (−1.75, 2.79) | 48% | |||
FPG | Participants condition | Type 2 diabetes | 5 | −16.28 (−33.02, 0.47) | 83% | 0.69 |
Other condition | 2 | −3.53 (−6.70, −0.37) | 0% | |||
Amount of apple vinegar | > 15 mL/day | 3 | −16.12 (−41.31, 9.07) | 87% | 0.15 | |
≤ 15 mL/day | 4 | −4.10 (−8.98, 0.76) | 52% | |||
Duration | >  8 weeks | 3 | −3.78 (− 6.90, −0.66) | 0% | 0.55 | |
≤ 8 weeks | 4 | −17.14 (−38.15, 3.86) | 86% | |||
HbA1C | Participants condition | Type 2 diabetes | 3 | −0.77 (−1.56, 0.02) | 88% | 0.001 |
Other condition | 3 | −0.07 (− 0.32, 0.18) | 0% | |||
Amount of apple vinegar | > 15 mL/day | 3 | −0.60 (−1.54, 0.33) | 92% | 0.13 | |
≤ 15 mL/day | 3 | −0.24 (− 0.51, 0.03) | 10% | |||
Duration | >  8 weeks | 3 | −0.72 (−1.58, 0.15) | 90% | 0.01 | |
≤ 8 weeks | 3 | −0.14 (− 0.43, 0.15) | 23% | |||