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Table 5 Biochemical parameters of rats after 28 days of treatment with HEASG

From: Toxicity and bacterial anti-motility activities of the hydroethanolic extract of Acacia senegal (L.) Willd (Fabaceae) leaves

Biochemical parameters

Sex

Control

250 mg/Kg

500 mg/Kg

1000 mg/Kg

Sodium (mmol/L)

F

139.4 ± 4.5

143.2 ± 5.9

139.0 ± 6.8

150.4 ± 2.5

M

139.2 ± 3.1

141.0 ± 3.3

146.23 ± 2.4

146.7 ± 1.3

Chloride (mmol/L)

F

121.0 ± 3.0

104.7 ± 1.5*

105.3 ± 4.0*

116.3 ± 6.4

M

122.0 ± 2.1

100.8 ± 3.3*

104.8 ± 1.0*

122.0 ± 3.0

Potassium (mmol/L)

F

5.4 ± 1.0

5.6 ± 1.2

5.0 ± 0.4

5.0 ± 0.6

M

5.8 ± 0.8

5.9 ± 0.4

5.0 ± 0.5

5.8 ± 0.6

Calcium (mmol/L)

F

3.5 ± 0.2

3.1 ± 0.1

3.1 ± 0.4

3.3 ± 0.2

M

3.4 ± 0.2

3.0 ± 0.1

3.1 ± 0.3

3.2 ± 0.1

Phosphorus (mmol/L)

F

3.9 ± 0.6

3.8 ± 0.3

3.5 ± 0.3

3.9 ± 0.6

M

4.5 ± 0.4

4.2 ± 0.3

3.7 ± 0.4

4.2 ± 0.3

ASAT (U/L)

F

133.7 ± 42

123.0 ± 30

129.8 ± 58

130.0 ± 34

M

129.0 ± 17

112.0 ± 28

129.0 ± 31

120.6 ± 27

ALAT (U/L)

F

36.5 ± 6.8

35.5 ± 3.1

34.3 ± 9.8

39.0 ± 9.4

M

43.6 ± 6.2

40.8 ± 6.5

38.0 ± 3.0

46.2 ± 6.0

Total protein (g/L)

F

61.8 ± 4.2

63.8 ± 4.1

62.5 ± 3.3

64.6 ± 3.1

M

61.5 ± 2.9

56.9 ± 1.2

61.0 ± 2.0

65.5 ± 3.1

Fasting blood glucose (mmol/L)

F

6.2 ± 0.8

4.6 ± 0.6

5.4 ± 0.1

5.4 ± 1.1

M

4.5 ± 0.7

4.4 ± 0.9

4.3 ± 1.2

4.4 ± 0.6

Creatinine (μmol/L)

F

67.5 ± 0.5

64.7 ± 2.9

62.0 ± 2.7

66.8 ± 1.2

M

60.1 ± 5.2

60.6 ± 6.3

56.8 ± 3.9

61.7 ± 4.9

Total cholesterol (mmol/L)

F

1.30 ± 0.30

1.20 ± 0.40

1.10 ± 0.05

1.30 ± 0.30

M

1.70 ± 0.20

1.30 ± 0.03

1.42 ± 0.05

1.50 ± 0.30

  1. Mean and standard deviation are represented (n = 10; 5/sex). M Male, F Female, * indicate statistically significant difference in values (p < 0.05) compared to control. Aspartate aminotransferase (AST); alanine aminotransferase (ALT)