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Table 2 Combinations tested in genotoxicity assay on J774A.1 macrophage cell

From: Immunomodulatory, trypanocide, and antioxidant properties of essential oil fractions of Lippia alba (Verbenaceae)

Mixture

Factorial combinations in CC50 Values

Compounds concentration

ACT1

ACT2

BNZ

ACT1 (μg/mL)

ACT2 (μg/mL)

BNZ (μg/mL)

3

1X CC50

2X CC50

 

458

426

4

2X CC50

1X CC50

 

916

213

5

4X CC50

½X CC50

 

1832

106.5

10

2X CC50

1X CC50

916

298.5

11

4X CC50

½X CC50

1832

149.3

12

8X CC50

0

3664

  1. ACT1 limonene-enriched fraction from Carvone-chemotype of Lippia alba, ACT2 citral/caryophyllene oxide enriched fraction from Citral-chemotype of Lippia alba, BZN Benznidazole, X Multiplier, CC50 Cytotoxic Concentration 50