Fig. 4

Representative functional response of common carotid artery at P = 60 mmHg. A Representative original tracings of functional curves induced by NE and SNP. B The histogram analysis of percentage of NE-induced contraction extent, * p < 0.05 vs SHR. C The histogram analysis of percentage of SNP-induced relaxation extent, * p < 0.05 vs SHR. D The histogram analysis of out diameter changes in different groups by NE and SNP, data in PSS is taken as the control. * p < 0.05 vs the same group in PSS, † p < 0.05 vs SHR group in NE, # p < 0.05 vs the same group in NE. (One-way ANOVA with Bonferroni post-hoc test)