Table 2 Top 5 genes from the subnetworks of each dataset based on their betweenness and degree centrality scores, depicting compound-specific signature genes in each cell line
ACT (MDA-MB-453) | CKI (MCF-7) | I3C (MCF-7) | I3C (MDA-MB-157) | I3C (MDA-MB-231) | I3C (MDA-MB-436) | I3C (T47D) | I3C (ZR751) | WA (MCF-7) | WA (MDA-MB-231) |
|---|---|---|---|---|---|---|---|---|---|
APP | ELAVL1 | TRIM25 | HNRNPL | HNRNPL | HNRNPL | HNRNPL | HNRNPL | APP | TRIM25 |
TRIM25 | HNRNPL | ELAVL1 | ESR2 | ELAVL1 | TRIM25 | TRIM25 | TRIM25 | TRIM25 | ELAVL1 |
ELAVL1 | APP | ESR2 | TRIM25 | ESR2 | ESR2 | ELAVL1 | ELAVL1 | ESR2 | APP |
ESR2 | TRIM25 | HNRNPL | CUL3 | CUL3 | ELAVL1 | ESR2 | APP | ELAVL1 | RNF4 |
HNRNPL | RNF4 | APP | BAG3 | CDH1 | APP | APP | RNF4 | HNRNPL | NXF1 |