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Table 6 AChE and BChE inhibitory potential of plant extracts

From: Phytochemical analysis and versatile in vitro evaluation of antimicrobial, cytotoxic and enzyme inhibition potential of different extracts of traditionally used Aquilegia pubiflora Wall. Ex Royle

Enzymes Sample   Concentration
25 μg/mL 50 μg/mL 100 μg/mL 200 μg/mL 400 μg/mL + control IC50
AChE APDW 31.7 ± 0.70*** 39.2 ± 0.66*** 47.5 ± 0.80*** 62.7 ± 1.2* 76.3 ± 1.1* 91.2 ± 2.1 193
APM 34.2 ± 0.81*** 44.6 ± 1.4** 51.7 ± 0.86* 59.1 ± 0.92* 68.5 ± 1.2* 87.1 ± 2.2 98
APE 27.8 ± 0.69*** 34.9 ± 0.61** 57.4 ± 0.92* 68.3 ± 1.2* 81.5 ± 1.6* 88.9 ± 1.9 91
APEA 27.6 ± 0.31*** 38.7 ± 0.50** 45.3 ± 0.73** 57.4 ± 0.81** 71.3 ± 0.81* 84.2 ± 1.7 163
BChE APDW 34.7 ± 0.93*** 42.2 ± 0.62** 49.7 ± 1.2** 66 ± 0.91* 77.4 ± 0.99* 91.6 ± 1.9 154
APM 31.9 ± 0.60*** 36.5 ± 0.48*** 42.7 ± 0.72** 61.1 ± 0.79* 72.1 ± 1.3* 90.3 ± 1.9 121
APE 38.2 ± 0.74*** 41.9 ± 0.59** 54.2 ± 1.4** 71.4 ± 0.93* 83.9 ± 1.4* 92.1 ± 1.8 84
APEA 31.1 ± 0.34** 43.1 ± 0.75** 57.3 ± 0.88* 61.6 ± 0.71* 67.1 ± 0.73* 87.3 ± 1.7 95
  1. Star *–*** represent; *** highly significant, ** slightly significant and * non-significant difference from the control at P < 0.05 by one-way ANOVA in the column. Values are mean ± SD of triplicate. Where APDW, APM, APE and APEA stands for Distilled water, Methanol, Ethanol and Ethyl acetate extracts, respectively