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Table 4 α-glucosidase and α-amylase inhibitory potential of different plant extracts

From: Phytochemical analysis and versatile in vitro evaluation of antimicrobial, cytotoxic and enzyme inhibition potential of different extracts of traditionally used Aquilegia pubiflora Wall. Ex Royle

Enzymes Sample Concentration
25 μg/mL 50 μg/mL 100 μg/mL 200 μg/mL 400 μg/mL
% inhibition
α-amylase APDW 17.83 ± 0.19** 26.22 ± 0.34** 29.05 ± 0.33** 32.03 ± 0.66** 37.43 ± 0.65**
APM 13.39 ± 0.17*** 17.61 ± 0.24*** 17.93 ± 0.31*** 23.81 ± 0.39*** 29.31 ± 0.48***
APE 22.82 ± 0.21* 31.08 ± 0.28* 37.83 ± 0.29* 51.26 ± 0.82* 55.38 ± 0.73*
APEA 12.37 ± 0.18*** 17.92 ± 0.19*** 21.28 ± 0.22*** 22.71 ± 0.30*** 27.23 ± 0.41***
+ control 27.78 ± 0.66 44.87 ± 0.93 59.43 ± 1.09 73.20 ± 1.51 89.40 ± 1.24
α-glucocidase APDW 14.94 ± 0.21* 20.61 ± 0.19* 22.91 ± 0.19** 30.51 ± 0.44* 34.14 ± 0.44**
APM 11.93 ± 0.20*** 16.72 ± 0.17** 20.17 ± 0.15** 20.52 ± 0.29** 24.63 ± 0.32***
APE 16.77 ± 0.34* 22.82 ± 0.21* 30.19 ± 0.43* 33.61 ± 0.31* 47.23 ± 0.41*
APEA 9.06 ± 0.11*** 14.98 ± 0.18** 16.28 ± 0.21*** 20.75 ± 0.27** 23.71 ± 0.31***
+ control 27.32 ± 0.73 33.4 ± 1.27 53.45 ± 1.11 65.98 ± 1.67 84.34 ± 1.92
  1. Star *–*** represent; *** highly significant, ** slightly significant and * non-significant difference from the control at P < 0.05 by one-way ANOVA in the column. Values are mean ± SD of triplicate. Where APDW, APM, APE and APEA stands for Distilled water, Methanol, Ethanol and Ethyl acetate extracts, respectively