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Table 4 α-glucosidase and α-amylase inhibitory potential of different plant extracts

From: Phytochemical analysis and versatile in vitro evaluation of antimicrobial, cytotoxic and enzyme inhibition potential of different extracts of traditionally used Aquilegia pubiflora Wall. Ex Royle

Enzymes

Sample

Concentration

25 μg/mL

50 μg/mL

100 μg/mL

200 μg/mL

400 μg/mL

% inhibition

α-amylase

APDW

17.83 ± 0.19**

26.22 ± 0.34**

29.05 ± 0.33**

32.03 ± 0.66**

37.43 ± 0.65**

APM

13.39 ± 0.17***

17.61 ± 0.24***

17.93 ± 0.31***

23.81 ± 0.39***

29.31 ± 0.48***

APE

22.82 ± 0.21*

31.08 ± 0.28*

37.83 ± 0.29*

51.26 ± 0.82*

55.38 ± 0.73*

APEA

12.37 ± 0.18***

17.92 ± 0.19***

21.28 ± 0.22***

22.71 ± 0.30***

27.23 ± 0.41***

+ control

27.78 ± 0.66

44.87 ± 0.93

59.43 ± 1.09

73.20 ± 1.51

89.40 ± 1.24

α-glucocidase

APDW

14.94 ± 0.21*

20.61 ± 0.19*

22.91 ± 0.19**

30.51 ± 0.44*

34.14 ± 0.44**

APM

11.93 ± 0.20***

16.72 ± 0.17**

20.17 ± 0.15**

20.52 ± 0.29**

24.63 ± 0.32***

APE

16.77 ± 0.34*

22.82 ± 0.21*

30.19 ± 0.43*

33.61 ± 0.31*

47.23 ± 0.41*

APEA

9.06 ± 0.11***

14.98 ± 0.18**

16.28 ± 0.21***

20.75 ± 0.27**

23.71 ± 0.31***

+ control

27.32 ± 0.73

33.4 ± 1.27

53.45 ± 1.11

65.98 ± 1.67

84.34 ± 1.92

  1. Star *–*** represent; *** highly significant, ** slightly significant and * non-significant difference from the control at P < 0.05 by one-way ANOVA in the column. Values are mean ± SD of triplicate. Where APDW, APM, APE and APEA stands for Distilled water, Methanol, Ethanol and Ethyl acetate extracts, respectively