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Table 1 Antimicrobial activity (MIC and MMC in μg/mL) of extracts and isolated compounds from R. abyssinicus as well as reference antimicrobial drugs

From: Antibacterial, antifungal and antioxidant activities of whole plant chemical constituents of Rumex abyssinicus

Extracts/ Compounds

Inhibition parameters

P. aeruginosa

S. flexneri

S. aureus

MSSA01

MRSA03

C. albicans

C. neoformans

MeOH extract

MIC

64

128

64

64

64

64

32

MMC

128

128

128

128

128

64

32

MMC/MIC

2

1

2

2

2

1

1

EtOAc fraction

MIC

64

32

32

64

64

32

32

MMC

128

32

64

64

64

64

32

MMC/MIC

2

1

2

1

1

2

1

n-BuOH fraction

MIC

128

128

128

256

256

64

32

MMC

256

256

128

256

256

64

64

MMC/MIC

2

2

1

1

1

1

2

1

MIC

64

32

32

64

64

64

32

MMC

128

32

64

64

128

64

32

MMC/MIC

2

1

2

1

2

1

1

2

MIC

8

8

8

16

16

8

8

MMC

16

16

8

32

32

8

8

MMC/MIC

2

2

1

2

2

1

1

3

MIC

128

128

256

>256

>256

128

64

 

MMC

256

>256

>256

>256

>256

>256

128

 

MMC/MIC

2

/

/

/

/

/

2

4

MIC

16

8

8

32

32

8

8

MMC

16

16

8

32

32

8

8

MMC/MIC

1

2

1

1

1

1

1

5

MIC

32

32

32

128

128

16

16

MMC

64

32

32

256

256

32

32

 

MMC/MIC

2

1

1

2

2

2

2

6 + 7

MIC

16

8

8

16

16

16

8

MMC

16

16

8

16

32

16

8

MMC/MIC

1

2

1

1

2

1

1

Refa

MIC

0.5

8

0.5

4

4

1

2

MMC

0.5

8

0.5

4

4

1

2

MMC/MIC

1

1

1

1

1

1

1

  1. /: not determined; MIC Minimum Inhibitory Concentration; MMC Minimum Microbicidal Concentration; a: fluconazole for yeasts and ciprofloxacin for bacteria