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Table 2 Effect of propolis at subinhibitory concentrations (0.05 and 0.1%) on CSH, adherence capacity and biofilm formation of C. glabrata (n = 12)

From: Antifungal and anti-biofilm activity of a new Spanish extract of propolis against Candida glabrata

Candida glabrata strains CSH (%) Adherence (OD) Biofilm (XTT-OD)
High CSH (Origin) Control 0.05% 0.10% Control 0.05% 0.10% Control 0.05% 0.10%
12 (H) 89.2 80.3 64.5 0.09 0.10 0.10 0.38 0.31 0.29
20 (H) 89.7 80.6 55.7 0.15 0.11 0.10 0.70 0.55 0.45
45 (H) 96.0 97.3 96.2 0.13 0.10 0.11 0.61 0.40 0.31
60 (E) 91.6 100.0 100.0 0.13 0.10 0.10 0.65 0.51 0,50
61 (E) 79.3 96.2 97.7 0.12 0.10 0.09
63 (S) 60.7 73.7 63.2 0.13 0.06 0.08 0.50 0.40 0.31
65 (P) 94.8 93.7 83.3 0.13 0.13 0.08
Median ± SD 85.9 ± 12.4 88.8 ± 10.4 80.1 ± 18.7 0.13 ± 0.02 0.10 ± 0.02 0.09 ± 0.01 0.57 ± 0.13 0.43 ± 0.10 0.37 ± 0.10
Medium CSH (Origin) Control 0.05% 0.10% Control 0.05% 0.10% Control 0.05% 0.10%
30 (H) 45.2 41.7 40.0 0.14 0.10 0.11 0.71 0.51 0.40
42 (H) 36.9 42.6 23.0 0.12 0.24 0.17 0.60 0.36 0.34
52 (H) 41.5 36.5 53.0 0.14 0.09 0.09 0.56 0.39 0.38
62 (H) 40.4 73.1 47.3 0.11 0.10 0.10 0.70 0.40 0.38
64 (V) 26.2 36.4 42.6 0.15 0.10 0.10
Median ± SD 38.0 ± 7.3 46.1 ± 16.2 41.2 ± 11.3 0.13 ± 0.02 0.13 ± 0.06 0.11 ± 0.03 0.64 ± 0.07 0.42 ± 0.07* 0.38 ± 0.03*
GLOBAL Median ± SD 66.0 ± 27 71.0 ± 25 63.9 ± 25 0.13 ± 0.02 0.11 ± 0.04 0.10 ± 0.02 0.60 ± 0.11 0.43 ± 0.08 0.37 ± 0.07*
  1. H Hemoculture; E Exudate; S Sputum; V Vaginal; P Preservation liquid; (−): No data; (*) p < 0.05