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Table 2 Effect of propolis at subinhibitory concentrations (0.05 and 0.1%) on CSH, adherence capacity and biofilm formation of C. glabrata (n = 12)

From: Antifungal and anti-biofilm activity of a new Spanish extract of propolis against Candida glabrata

Candida glabrata strains

CSH (%)

Adherence (OD)

Biofilm (XTT-OD)

High CSH (Origin)

Control

0.05%

0.10%

Control

0.05%

0.10%

Control

0.05%

0.10%

12 (H)

89.2

80.3

64.5

0.09

0.10

0.10

0.38

0.31

0.29

20 (H)

89.7

80.6

55.7

0.15

0.11

0.10

0.70

0.55

0.45

45 (H)

96.0

97.3

96.2

0.13

0.10

0.11

0.61

0.40

0.31

60 (E)

91.6

100.0

100.0

0.13

0.10

0.10

0.65

0.51

0,50

61 (E)

79.3

96.2

97.7

0.12

0.10

0.09

63 (S)

60.7

73.7

63.2

0.13

0.06

0.08

0.50

0.40

0.31

65 (P)

94.8

93.7

83.3

0.13

0.13

0.08

Median ± SD

85.9 ± 12.4

88.8 ± 10.4

80.1 ± 18.7

0.13 ± 0.02

0.10 ± 0.02

0.09 ± 0.01

0.57 ± 0.13

0.43 ± 0.10

0.37 ± 0.10

Medium CSH (Origin)

Control

0.05%

0.10%

Control

0.05%

0.10%

Control

0.05%

0.10%

30 (H)

45.2

41.7

40.0

0.14

0.10

0.11

0.71

0.51

0.40

42 (H)

36.9

42.6

23.0

0.12

0.24

0.17

0.60

0.36

0.34

52 (H)

41.5

36.5

53.0

0.14

0.09

0.09

0.56

0.39

0.38

62 (H)

40.4

73.1

47.3

0.11

0.10

0.10

0.70

0.40

0.38

64 (V)

26.2

36.4

42.6

0.15

0.10

0.10

Median ± SD

38.0 ± 7.3

46.1 ± 16.2

41.2 ± 11.3

0.13 ± 0.02

0.13 ± 0.06

0.11 ± 0.03

0.64 ± 0.07

0.42 ± 0.07*

0.38 ± 0.03*

GLOBAL Median ± SD

66.0 ± 27

71.0 ± 25

63.9 ± 25

0.13 ± 0.02

0.11 ± 0.04

0.10 ± 0.02

0.60 ± 0.11

0.43 ± 0.08

0.37 ± 0.07*

  1. H Hemoculture; E Exudate; S Sputum; V Vaginal; P Preservation liquid; (−): No data; (*) p < 0.05