Fig. 2

The effect of ICAR on viability, apoptosis and inflammatory damage of OA in vitro model. a and b The chondrocytes stimulated by IL-1β were treated with 0, 10, 20, 30 μM ICAR, respectively, and the cell viability was detected by CCK-8. c The chondrocytes stimulated by IL-1β were treated with 0, 10, 20, 30 μM ICAR, respectively, and the apoptosis was detected by flow cytometry. d-f The chondrocytes stimulated by IL-1β were treated with 0,10,20,30 μM ICAR, respectively, and the contents of IL-6, IL-8 and TNF-α were detected by ELISA. *P < 0.05, **P < 0.01, ***P < 0.001 vs. control group