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Table 3 Percentage (%) and relative concentrations (μg/mL) of the compounds of different chemotype thyme oils

From: Three chemotypes of thyme (Thymus vulgaris L.) essential oil and their main compounds affect differently the IL-6 and TNFα cytokine secretions of BV-2 microglia by modulating the NF-κB and C/EBPβ signalling pathways

  

Percentage of compound in the thyme chemotypesa

Relative concentration of compound in the experimentsb (μg/mL)

Compound

LRI

Geraniol

Thujanol

Linalool

Geraniol

Thujanol

Linalool

α-Thujene

930

ND

0.4

0.6

ND

0.018

0.028

α-Pinene

939

0.1

1.2

1.4

0.004

0.051

0.061

Camphene

951

0.3

0.2

0.4

0.012

0.0084

0.017

1-Octen-3-ol

978

0.1

ND

ND

0.004

ND

ND

β-Myrcene

979

0.1

0.7

1.0

0.004

0.028

0.04

β-Pinene

992

ND

0.4

0.1

ND

0.017

0.004

α-Phellandrene

1003

ND

1.2

0.1

ND

0.051

0.004

α-Terpinene

1017

ND

1.4

0.1

ND

0.059

0.004

p-Cymene

1026

0.2

2.1

4.2

0.009

0.090

0.18

Limonene

1029

0.1

1.8

1.3

0.004

0.076

0.055

1,8-Cineole

1046

0.2

0.4

0.9

0.009

0.018

0.041

γ-Terpinene

1060

0.1

2.9

1.3

0.004

0.123

0.055

Terpinolene

1093

ND

0.7

1.2

ND

0.031

0.052

Linalool

1104

3.0

8.4

69.2

0.128

0.361

2.736

Myrcenol

1123

0.1

3.2

ND

0.004

0.136

ND

cis-β-Terpineol

1144

0.2

ND

1.5

0.009

ND

0.007

Verbenol

1145

ND

0.2

0.1

ND

0.001

0.001

Camphor

1146

0.1

0.1

1.2

0.005

0.005

0.059

trans-Thujanol

1154

ND

33.9

ND

ND

0.616

ND

cis-Thujanol

1159

ND

6.5

ND

ND

0.033

ND

trans-β-Terpineol

1163

ND

0.8

0.1

ND

0.037

0.005

Borneol

1169

1.5

0.4

2.3

0.008

0.002

0.012

Terpinen-4-ol

1177

0.6

11.9

8.3

0.028

0.555

0.373

α-Terpineol

1190

ND

4.3

1.8

ND

0.204

0.084

trans- Piperitol

1208

ND

0.1

0.5

ND

0.005

0.024

Nerol

1230

1.9

4.2

0.1

0.084

0.185

0.004

Neral

1238

0.8

ND

ND

0.035

ND

ND

Geraniol

1253

54.9

1.9

ND

2.193

0.083

ND

Linalyl acetate

1257

0.3

2.9

0.6

0.013

0.130

0.027

Geranial

1267

1.3

ND

ND

0.058

ND

ND

Bornyl acetate

1289

0.2

ND

ND

0.010

ND

ND

Thymol

1297

1.4

0.7

0.9

0.067

0.034

0.043

Carvacrol

1299

0.7

ND

ND

0.034

ND

ND

Neryl acetate

1365

0.2

ND

ND

0.009

ND

ND

Geranyl acetate

1381

18.6

0.7

ND

0.851

0.032

ND

β-Caryophyllene

1417

5.7

4.0

0.6

0.3

0.180

0.027

α-Humulene

1452

0.1

ND

ND

0.004

ND

ND

Geranyl propionate

1486

2.2

ND

ND

0.099

ND

ND

Germacrene D

1486

ND

0.8

ND

ND

0.032

ND

Geranyl isobutyrate

1515

0.3

ND

ND

0.013

ND

ND

Elemol

1550

2.2

ND

ND

0.103

ND

ND

Caryophyllene oxide

1583

1.4

0.6

ND

0.067

0.029

ND

β-Eudesmol

1651

0.4

ND

ND

0.019

ND

ND

Total:

 

99.3

99.0

99.8

   
  1. aLRI - linear retention index on SLB-5MS column
  2. bThe relative concentrations were chosen based on the calculation as if the cells were treated with 200 μL essential oil