Three chemotypes of thyme (Thymus vulgaris L.) essential oil and their main compounds affect differently the IL-6 and TNFα cytokine secretions of BV-2 microglia by modulating the NF-κB and C/EBPβ signalling pathways

Table 2 Percentage (%) and relative concentrations (μg/mL) of the main compounds of different chemotype thyme oils used in the experiments and the dilution of the main oil compounds without cytotoxic effect

Compound	LRI	Percentage of compound in the oil^a	Relative concentration of compound in the experiments^b (μg/mL)	Dilution of compound without cytotoxic effect
Geraniol	1253	54.9	2.1	200
Linalool	1104	69.2	2.7	200
Thujanol	1154	33.9	0.6	200

^aLRI - linear retention index on SLB-5MS column
^bThe relative concentrations were chosen based on the calculation as if the cells were treated with 200 μL essential oil

ISSN: 2662-7671