Fig. 1

HPP increased the expression levels of inflammatory cytokines, such as IL-1β and NO, secreted by macrophages and promoted the expression of surface molecules CD86 and CD16. a-b mRNA expression of IL-1β, and iNOS in macrophages after 6 h of HPP or LPS incubation. c-d HPP or LPS induced IL-1β and TNF-α production in the cell supernatant and the expression levels cytokines were analyzed by ELISA. e-h THP-1-derived macrophages were pretreated with HPP or LPS for 72 h, then the expression levels of CD23, CD40, CD16, and CD86 were measured by flow cytometry. ^*P < 0.05; ^**P < 0.01 compared with the control group(n = 3)