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Fig. 7 | BMC Complementary Medicine and Therapies

Fig. 7

From: Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences

Fig. 7

Echinaforce® treatment leads to global hypermethylation of intergenic repeat elements. a Genomic enrichment of DMPs in different repeat elements. b Global DNA methylation changes in different repeat elements. c HERV qPCR gene expression. THP1 cells were with Echinaforce® at 12 and 48 h (n = 3). Mean LogFC change relative to solvent control is represented together with 95% confidence interval. *: P ≤ 0.05, ** P: ≤ 0.01, *** P: ≤ 0.001 and **** P: ≤ 0.0001

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