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Fig. 2 | BMC Complementary Medicine and Therapies

Fig. 2

From: Echinacea purpurea (L.) Moench treatment of monocytes promotes tonic interferon signaling, increased innate immunity gene expression and DNA repeat hypermethylated silencing of endogenous retroviral sequences

Fig. 2

Protein-protein-interaction network analysis of Echinaforce® treatment responsive genes. STRING based protein-protein-interaction network analysis of differentially expressed genes of THP1 cells treated for 48 h with Echinaforce® tincture (1%) shows a strong network overlap of the cellular response to a chemical stimulus (FDR 2,91 E-18) (blue colored dots-pies), cellular defense to virus (FDR 5,54 E-19) (red colored dots-pies) and innate immune cytokine response (FDR 2,23 E-18) (yellow colored dots-pies) (see also, supplementary Table 4)

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