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Table 2 Effect of CPCM on oral glucose tolerance test, glycosylated hemoglobin, C-peptide and insulin resistance index in db/db mice

From: The beneficial effects of the composite probiotics from camel milk on glucose and lipid metabolism, liver and renal function and gut microbiota in db/db mice

 

Normal (n=10)

Model (n=9)

Metoformin (n=10)

Low dose (n=10)

High dose (n=10)

0min (mmol/L)

6.69±0.71

25.88±6.19***

13.10±3.86###

19.12±5.87

18.03±4.46#

30min (mmol/L)

15.70±2.50

39.11±4.34***

31.51±6.57#

37.23±4.00

35.58±5.07

60min (mmol/L)

11.98±1.86

36.19±8.55***

24.53±4.49#

31.39±6.93

27.47±4.12#

120min (mmol/L)

7.65±2.35

26.59±6.52***

16.19±4.52##

19.41±3. 77#

18.15±4.49#

AUC

1308.81±76.55

3780.06±671.58***

2703.04±431.49#

3314.28±544.60

3152.50±371.34

glycosylated hemoglobin (ng/ml)

7.78±1.99

17.27±1.01***

12.33±1.44###

15.74±1.27#

15.28±2.04#

C-peptide (mmol/L)

2.51±0.36

2.19±0.16*

2.53±0.45#

2.40±0.19#

2.52±0.31#

insulin resistance index

3.44±0.22

8.21±1.24***

5.25±1.25##

6.42±1.20#

6.29±1.01#

  1. *P <0.05, ***P <0.001 vs normal group; # P <0.05, ## P <0.01, and ### P <0.001 vs model group