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Table 7 Genotoxicity of selected methanol extracts against Salmonella Typhimurium strains (TA98 and TA100) presented as mean ± standard error

From: In vitro antibacterial activity of Loxostylis alata extracts and isolated compounds against Salmonella species

Plant species

Dose (mg/mL)

Histidine + revertant colonies

TA98

TA100

Kirkia wilmsii

5

29.50 ± 0.50

156.00 ± 2.00

0.5

23.67 ± 2.96

145.67 ± 2.60

0.05

23.33 ± 0.33

126.00 ± 14.00

Loxostylis alata

5

25.67 ± 2.85

201.50 ± 5.50

0.5

24.67 ± 0.88

188.50 ± 6.50

0.05

20.33 ± 0.88

145.33 ± 2.33

Protorhus longifolia

5

23.33 ± 5.17

163.00 ± 5.00

0.5

21.00 ± 1.00

135.50 ± 4.50

0.05

23.50 ± 1.50

142.33 ± 8.69

Searsia leptodictya

5

24.67 ± 2.40

172.00 ± 6.00

0.5

22.33 ± 1.20

157.00 ± 7.00

0.05

21.67 ± 1.45

109.00 ± 16.00

4-NQO (+ve C)

 

316.67 ± 7.42

766.00 ± 1.46

10% DMSO (−ve C)

 

24.67 ± 2.40

158.00 ± 3.04

Water (−ve C)

 

24.33 ± 2.73

171.00 ± 1.50

  1. M methanol extract, 4-NQO 4-nitroquinoline-1-oxide, DMSO Dimethyl sulfoxide, +ve C Positive control, −ve C Negative control