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Table 4 Physicochemical and toxicological properties of the compounds for good oral bioavailability

From: Antidiarrheal, antimicrobial and antioxidant potentials of methanol extract of Colocasia gigantea Hook. f. leaves: evidenced from in vivo and in vitro studies along with computer-aided approaches

Compounds

Molecular Weight (M.W) (g/mol)

H-bond Donor

H-bond Acceptors

Lipophilicity - log P (o/w)

GI Absorption

AMES Toxicity

Carcinogens

Rat Acute Toxicity

Loperamide

477.04

1

3

4.13

High

No

No

3.6560

Amoxicillin

365.40

4

6

1.22

Low

No

No

1.7036

Alpha-Amyrin

426.72

1

1

4.77

Low

No

No

2.0842

Beta-Amyrin

426.72

1

1

4.75

Low

No

No

2.0842

Monoglyceryl stearic acid

358.56

2

4

4.59

High

No

No

0.8172

Penduletin

344.32

2

7

2.84

High

No

No

3.1579