Fig. 4

TCS and GrzB inhibits tumor cell proliferation and induces apoptosis. a, b. TUNEL positive signals were significantly increased by the treatment of GrzB and TCS promoted the apoptotic cell death of tumor cells (TUNEL: green; DAPI: blue). Bar = 100 μm c, d. Ki67 positive signals were significantly decreased by the treatment of GrzB and TCS inhibited the proliferation of tumor cells (Ki67: green; DAPI: blue). Data are expressed as mean ± standard error of the mean. Bar = 50 μm. *, p < 0.05; **, p < 0.01