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Table 1 Inhibition properties of DME in protein denaturation and membrane stabilization (both hypotonicity and heat induced) as compared to negative control group

From: Validating potent anti-inflammatory and anti-rheumatoid properties of Drynaria quercifolia rhizome methanolic extract through in vitro, in vivo, in silico and GC-MS-based profiling

Test samples Concentration (μg/ml) Mean% of inhibition of haemolysis ± S.D
Protein denaturation test Hypotonicity induced Heat induced
DME 600 29 ± 6.34 *** 36.5 ± 7.3*** 8.37 ± 1.24**
800 39.6 ± 6.46 *** 52.1 ± 4.22*** 24.6 ± 3.21***
1000 51.2 ± 4.41*** 61.1 ± 4.81*** 31.9 ± 3.35***
a Diclofenac 100 62.8 ± 9.79***
b Indomethacin 200 76.3 ± 5.82*** 43.9 ± 3.03***
  1. ***indicates p ≤ 0.001, **indicates p ≤ 0.01, and *indicates p ≤ 0.05
  2. a Diclofenac served as a standard drug for anti-protein denaturation agents
  3. b Indomethacin served standard drug for a membrane stabilizing activity