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Table 1 Cytotoxicity of AA against human lung cancer and human bronchial epithelial cell lines

From: Antitumor activities of Aspiletrein A, a steroidal saponin from Aspidistra letreae, on non-small cell lung cancer cells

Lung cancer cell lines aIC50 (μM ± SD) Bronchial epithelial cell line aIC50 (μM ± SD) bSI
H460 15.13 ± 4.86 BEAS-2B 23.09 ± 4.08 1.72
H23 10.10 ± 2.93    2.58
A549 8.78 ± 3.08    2.97
  1. aConcentration that inhibits cell viability by 50%. bSelectivity index = IC50 of normal cells/IC50 of cancer cells [28]