Tannins extract from Galla Chinensis can protect mice from infection by Enterotoxigenic Escherichia coli O101

Table 2 The diarrhea index in each group

Group	Day 4	Day 5	Day 6	Day 7
Normal	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00
Negative control	2.87 ± 0.59	1.26 ± 0.31	0.25 ± 0.16	0.00 ± 0.00
Loperamide	1.51 ± 0.52 ^*	0.11 ± 0.09 ^**	0.00 ± 0.00^*	0.00 ± 0.00
GOS 5%	2.06 ± 0.24 ^a	0.22 ± 0.24 ^**	0.00 ± 0.00^*	0.00 ± 0.00
GOS 10%	1.64 ± 0.41 ^*a	0.15 ± 0.04 ^**	0.00 ± 0.00^*	0.00 ± 0.00
GOS 15%	1.18 ± 0.33 ^**b	0.06 ± 0.04 ^**	0.00 ± 0.00^*	0.00 ± 0.00

Normal, the uninfected-untreated control. Negative control, the infected-untreated control. Loperamide, the infected group with Loperamide-treatment (10 mg/kg). The 5, 10 and 15% GOS were the infected groups treated with corresponding concentration of GOS at a dose of 10 mL/kg, respectively. ^* P < 0.05 and ^** P < 0.01, compared with the negative control. ^{a, b} Different letters indicate significant differences existed among the three GOS groups (P < 0.05). Data are presented as mean ± S.E.M. n = 16

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