Fig. 6
Inflammatory, Th1 and Th2 cytokines after MCM treatment in mice with DNCB-induced AD-like skin lesions in blood serum. The serum level of cytokines was measured with Bioplex Multiplex Bead array system. a IL-1β. b IL-2. c IL-6. d TNF-α. e IL-12 (p70). f IFN-γ. g IL-4. h IL-10. NC: normal control group without any treatment, DNCB only: negative control group treated with DNCB only, PC: positive control group treated with DNCB and tacrolimus ointment, and MCM: experimental group treated with DNCB and MCM patch. Data are expressed as mean ± SD for 8 mice. Significance difference was analyzed with ANOVA and Tukey’s test. *p < 0.05, **p < 0.01, ***p < 0.001