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Table 3 Log HA titer and cell viability results of the combined treatments of Newtonia species extracts and isolated compound compared to H1N1 only

From: Anti-influenza A virus activity of two Newtonia species and the isolated compound myricetin-3-o-rhamnoside

Treatment

Log HA titre

Cell Viability (ratio to control)

H1N1 with no extract

Virus inoculation

2.408

0.169 ± 0.010

Extracts combined with H1N1

Nh1

0**

0.887 ± 0.111*

Nh2

0**

0.860 ± 0.165*

Nh3

0**

0.683 ± 0.078*

Nh4

0**

0.679 ± 0.032*

Nb1

0**

0.684 ± 0.051*

Nb2

0**

0.719 ± 0.026*

Nb3

0**

0.729 ± 0.012*

Nb4

0**

0.711 ± 0.014*

Compound in co-penetration treatment with virus

J2S

0**

0.601 ± 0.043*

  1. N. hildebrandtii acetone leaf extract (Nh1), N. hildebrandtii Methanol-DCM leaf extract (Nh2), N. hildebrandtii acetone stem extract (Nh3) N. hildebrandtii Methanol-DCM stem extract (Nh4), N. buchananii acetone leaf extract (Nb1), N. buchananii Methanol-DCM leaf extract (Nb2), N. buchananii acetone stem extract (Nb3) N. buchananii Methanol-DCM stem extract (Nb4), J2S (isolated myricetin-3-O-rhamnoside)
  2. The stars show the significant level between the values of combined treatments and H1N1; *: significant, **: highly significant