Fig. 2

Measuring tubulogenesis capacity of CSCs on Matrigel substrate (a-b). The inhibitory effect of 10, 30 ϻM TQ was studied on MDA-MB-321 CSCs. Bright-field images showed the inhibition of tubulogenesis activity in CSCs after being-exposed to TQ. Black arrows: cell budding; small yellow arrows: anastomosis. One-Way ANOVA with Tukey posthoc analysis. *p < 0.05, **p < 0.01; ***p < 0.001 and ****p < 0.0001