Fig. 2

Effect of CETC on LPS induced nuclear translocation of NF-κB in THP-1 macrophages. NF-κB that becomes typically sequestered in the cytoplasm (normal and DMSO control panel) gets concentrated to the nucleus following LPS (1 μg/ml) stimulation (LPS panel), a hallmark of the molecular inflammatory process. But 100 μg/ml CETC pre-treatment actively prevented the nuclear shift of NF-κB which was then found to be distributed all over the cytoplasm (100 μg/ml treated panel) following LPS (1 μg/ml) provocation