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Table 4 List of the top 20 down-regulated DEGs (DSEH group vs. Blank group)

From: The enzymatic hydrolysates from deer sinew promote MC3T3-E1 cell proliferation and extracellular matrix synthesis by regulating multiple functional genes

Gene name Blank (FPKM) DSEH (FPKM) log2 fold change (DSEH /Blank) P value
Metallothionein-1 (Mt1) 419.48 188.65 −1.15 6.40E-107
Non-histone chromosomal protein HMG-17 (Hmgn2) 310.59 145.14 −1.10 4.58E-176
Prolactin-2C2 (Prl2c2) 302.57 105.30 −1.52 9.84E-167
Cell division cycle protein 20 homolog (Cdc20) 118.90 57.15 −1.06 3.10E-94
Prolactin-2C3 (Prl2c3) 166.68 55.41 −1.59 1.69E-109
Transmembrane glycoprotein NMB (Gpnmb) 76.68 30.90 −1.31 1.28E-184
Neuropilin-2 (Nrp2) 45.13 22.36 −1.01 2.48E-107
Muscleblind-like protein 1 (Mbnl1) 58.40 19.94 −1.55 6.30E-240
Growth arrest-specific protein 1 (Gas1) 48.10 17.13 −1.49 5.60E-116
Protein PRRC2C (Prrc2c) 31.70 15.05 −1.07 1.73E-153
Monofunctional C1-tetrahydrofolate synthase, mitochondrial (Mthfd1l) 30.62 14.72 −1.06 6.77E-53
Sodium/potassium/calcium exchanger 3 (Slc24a3) 29.19 14.47 −1.01 7.42E-50
Protein DEK (Dek) 29.00 13.78 −1.07 5.39E-36
Semaphorin-3A (Sema3a) 27.29 13.47 −1.02 4.21E-85
High mobility group protein HMGI-C (Hmga2) 34.31 13.10 −1.39 1.50E-35
Mannose-P-dolichol utilization defect 1 protein (Mpdu1) 25.49 12.73 −1.00 1.24E-14
Lymphocyte-specific helicase (Hells) 25.43 11.80 −1.11 7.89E-39
CKLF-like MARVEL transmembrane domain-containing protein 3 (Cmtm3) 30.93 11.47 −1.43 5.24E-36
Homeobox protein engrailed-1 (En1) 32.58 11.37 −1.52 1.05E-65
Small subunit processome component 20 homolog (Utp20) 27.90 11.06 −1.33 1.98E-163
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