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Table 3 List of the top 20 up-regulated DEGs (DSEH group vs. Blank group)

From: The enzymatic hydrolysates from deer sinew promote MC3T3-E1 cell proliferation and extracellular matrix synthesis by regulating multiple functional genes

Gene name Blank (FPKM) DSEH (FPKM) log2 fold change (DSEH /Blank) P value
Glutathione S-transferase P1 (Gstp1) 367.61 855.07 1.22 2.30E-308
Metalloproteinase inhibitor 1 (Timp1) 286.17 601.03 1.07 2.54E-223
Plasminogen activator inhibitor 1 (Serpine1) 131.49 550.47 2.07 0
Protein CYR61 (Cyr61) 153.48 444.08 1.53 0
H-2 class I histocompatibility antigen, D-B alpha chain (H2d1) 173.13 359.46 1.05 2.90E-274
Connective tissue growth factor (Ctgf) 28.09 357.75 3.67 0
Radiation-inducible immediate-early gene IEX-1 (Ier3) 76.23 338.48 2.15 0
Cytokine receptor-like factor 1 (Crlf1) 75.46 270.42 1.84 0
Thrombospondin-1 (Thbs1) 94.94 248.54 1.39 0
Metalloproteinase inhibitor 3 (Timp3) 69.64 214.57 1.62 0
Thioredoxin reductase 1, cytoplasmic (Txnrd1) 98.89 206.75 1.06 0
Host cell factor C1 regulator 1 (Hcfc1r1) 80.00 206.17 1.37 8.01E-166
Cysteine and glycine-rich protein 2 (Csrp2) 91.15 201.85 1.15 1.22E-83
Serine protease HTRA1 (Htra1) 98.34 200.55 1.03 8.28E-177
Rho-related GTP-binding protein RhoB (Rhob) 78.30 199.78 1.35 3.74E-304
Thioredoxin-interacting protein (Txnip) 26.89 175.95 2.71 0
Heme transporter HRG1 (Slc48a1) 67.54 157.59 1.22 1.89E-230
Annexin A6 (Anxa6) 62.46 148.03 1.24 9.92E-235
Flavin reductase (NADPH)(Blvrb) 47.91 142.93 1.58 9.87E-95
Proline-rich protein 13 (Prr13) 47.48 135.82 1.52 1.47E-117
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