Table 3 List of the top 20 up-regulated DEGs (DSEH group vs. Blank group)
Gene name | Blank (FPKM) | DSEH (FPKM) | log2 fold change (DSEH /Blank) | P value |
|---|---|---|---|---|
Glutathione S-transferase P1 (Gstp1) | 367.61 | 855.07 | 1.22 | 2.30E-308 |
Metalloproteinase inhibitor 1 (Timp1) | 286.17 | 601.03 | 1.07 | 2.54E-223 |
Plasminogen activator inhibitor 1 (Serpine1) | 131.49 | 550.47 | 2.07 | 0 |
Protein CYR61 (Cyr61) | 153.48 | 444.08 | 1.53 | 0 |
H-2 class I histocompatibility antigen, D-B alpha chain (H2d1) | 173.13 | 359.46 | 1.05 | 2.90E-274 |
Connective tissue growth factor (Ctgf) | 28.09 | 357.75 | 3.67 | 0 |
Radiation-inducible immediate-early gene IEX-1 (Ier3) | 76.23 | 338.48 | 2.15 | 0 |
Cytokine receptor-like factor 1 (Crlf1) | 75.46 | 270.42 | 1.84 | 0 |
Thrombospondin-1 (Thbs1) | 94.94 | 248.54 | 1.39 | 0 |
Metalloproteinase inhibitor 3 (Timp3) | 69.64 | 214.57 | 1.62 | 0 |
Thioredoxin reductase 1, cytoplasmic (Txnrd1) | 98.89 | 206.75 | 1.06 | 0 |
Host cell factor C1 regulator 1 (Hcfc1r1) | 80.00 | 206.17 | 1.37 | 8.01E-166 |
Cysteine and glycine-rich protein 2 (Csrp2) | 91.15 | 201.85 | 1.15 | 1.22E-83 |
Serine protease HTRA1 (Htra1) | 98.34 | 200.55 | 1.03 | 8.28E-177 |
Rho-related GTP-binding protein RhoB (Rhob) | 78.30 | 199.78 | 1.35 | 3.74E-304 |
Thioredoxin-interacting protein (Txnip) | 26.89 | 175.95 | 2.71 | 0 |
Heme transporter HRG1 (Slc48a1) | 67.54 | 157.59 | 1.22 | 1.89E-230 |
Annexin A6 (Anxa6) | 62.46 | 148.03 | 1.24 | 9.92E-235 |
Flavin reductase (NADPH)(Blvrb) | 47.91 | 142.93 | 1.58 | 9.87E-95 |
Proline-rich protein 13 (Prr13) | 47.48 | 135.82 | 1.52 | 1.47E-117 |