Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway

Nie, Fujiao; Yan, Jiazhao; Ling, Yanjun; Liu, Zhengrong; Fu, Chaojun; Li, Xiang; Qin, Yuhui

doi:10.1186/s12906-021-03238-w

BMC Complementary Medicine and Therapies

Table 1 Molecular information of ingredients absorbed into plasma of SDMM capsule

From: Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway

NO.	Compound	Molecular formula	Source
1	L-Tyrosine tert-butyl ester	C₁₃H₁₉NO₃	Cornus officinalis Sieb. et Zucc.
2	Sarracenin	C₁₁H₁₄O₅	Cornus officinalis Sieb. et Zucc.
3	Sugiol	C₂₀H₂₈O₂	Salvia miltiorrhiza Bunge
4	Cryptotanshinone	C₁₉H₂₀O₃	Salvia miltiorrhiza Bunge
5	3,4-Dihydroxybenzoic acid	C₇H₆O₄	Alisma plantago-aquatica L.
6	N-Acetyl-L-proline	C₇H₁₁NO₃	Cornus officinalis Sieb. et Zucc.
7	2-cyclohexylethyl-beta-D-maltoside	C₂₀H₃₆O₁₁	Eclipta prostrata (L.) L.
8	Paeonilactone B	C₁₀H₁₂O₄	Paeonia suffruticosa Andr.
9	Apigenin	C₁₅H₁₀O₅	Eclipta prostrata (L.) L.
10^a	D-ring-opening metabolites of cryptotanshinone	C₁₉H₂₂O₄	Salvia miltiorrhiza Bunge
11	5-Allyl-1,3-bis (methoxymethyl)-5-(1-methylbutyl) barbituric acid	C₁₆H₂₆N₂O₅	Dioscorea polystachya Turczaninow
12	Loliolide	C₁₁H₁₆O₃	Eclipta prostrata (L.) L. (mohanlian,
13	Pachymic acid C	C₃₁H₄₆O₄	Poria cocos (Schw.) Wolf.
14	Loganin	C₁₇H₂₆O₁₀	Cornus officinalis Sieb. et Zucc.
15	Coniferylaldehyde	C₁₀H₁₀O₃	Eclipta prostrata (L.) L.
16	Loganetin	C₁₁H₁₆O₅	Cornus officinalis Sieb. et Zucc.
17	Catalpin	C₁₃H₂₀O₉	Eclipta prostrata (L.) L.
18	Eriodictyol	C₁₅H₁₂O₆	Eclipta prostrata (L.) L.
19	Albiflorin	C₂₃H₂₈O₁₁	Paeonia suffruticosa Andr.
20	Cosmosiin	C₂₁H₂₀O₁₀	Ligustrum lucidum Ait.
21	Resveratrol	C₁₄H₁₂O₃	Smilax glabra Roxb.
22	Oriediterpenoside	C₂₅H₄₀O₆	Alisma plantago-aquatica L.
23	7-O-Methyl morroniside	C₁₈H₂₈O₁₁	Cornus officinalis Sieb. et Zucc.
24	oleanolic acid acetate	C₃₂H₅₀O₄	Achyranthes bidentata Blume
25	Cornuside	C₂₄H₃₀O₁₄	Cornus officinalis Sieb. et Zucc.
26	Oleanic acid	C₃₀H₄₈O₃	Eclipta prostrata (L.) L.
27^a	Glucuronic acid conjugates of protocatechol	C₆H₁₀O₇	Alisma plantago-aquatica L.
28^a	Glycine conjugates of Danshensu	C₉H₁₀O₅	Salvia miltiorrhiza Bunge
29	Nuezhengalaside	C₁₈H₂₈O₉	Eclipta prostrata (L.) L.
30	Ecliptin	C₃₆H₅₈O₈	Eclipta prostrata (L.) L.
31	Acetylursolic acid	C₃₂H₅₂O₄	Poria cocos (Schw.) Wolf.
32	Skullcapflavone II	C₁₉H₁₈O₈	Eclipta prostrata (L.) L.
33	Alisol A	C₃₀H₅₀O₅	Alisma plantago-aquatica L.
34	Luteolin	C₁₅H₁₀O₆	Eclipta prostrata (L.) L.
35	Isocryptotanshinone	C₁₉H₂₀O₃	Salvia miltiorrhiza Bunge
36	Tanshinone IIA	C₁₉H₁₈O₃	Salvia miltiorrhiza Bunge

(^a: Metabolites)

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