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Fig. 8 | BMC Complementary Medicine and Therapies

Fig. 8

From: Effect of Shuangdan Mingmu capsule, a Chinese herbal formula, on oxidative stress-induced apoptosis of pericytes through PARP/GAPDH pathway

Fig. 8

RT-qPCR (n = 3). RT-qPCR was performed to determine mRNA expression of eNOS, SOD, ET1, VEGFA, BCL2, PARP1, and GAPDH. a is the heatmap (−△△CT) and (b,c,d) display the fold change (2-△△CT) of those gene. It’s clearly shown that eNOS, SOD, BCL2, and GAPDH were downregulated in Control group, whereas, ET1, VEGFA, and PARP1 were upregulated in Control group. SDMM showed dose-dependent ability to resist above regulations. (**: versus Control group, P<0.01; *: versus Control group, P<0.05; n.s.:versus Control group, P>0.05)

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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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