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Table 1 Effect of nanoemulsion treatment on biochemical parameters of rats’ serum during the acute dermal toxicity study

From: Anti-osteoarthritis potential of peppermint and rosemary essential oils in a nanoemulsion form: behavioral, biochemical, and histopathological evidence

 

Control

Nanoemulsion

Male (n = 3)

Mean ± SEM

Female (n = 3)

Mean ± SEM

Male (n = 3)

Mean ± SEM

Female (n = 3)

Mean ± SEM

WBC

11.13 ± 0.23

9.07 ± 0.35

11.27 ± 0.32

8.83 ± 0.27

RBC

7.72 ± 0.95

7.27 ± 0.15

7.73 ± 0.18

7.43 ± 0.2

HGB

14.37 ± 0.12

13.23 ± 0.15

14.37 ± 0.2

13.37 ± 0.2

HCT

46.2 ± 1.33

42.73 ± 1.27

45.73 ± 1.78

42.9 ± 1.5

MCV

54.37 ± 1.21

52.33 ± 0.85

54.73 ± 1.16

52.17 ± 1.13

MCH

17.03 ± 0.88

17.7 ± 0.35

17.2 ± 0.21

18.1 ± 0.25

MCHC

33 ± 0.23

33.27 ± 0.55

32.77 ± 0.65

34.43 ± 0.87

PLT

1085.33 ± 20.54

1063.67 ± 20.04

1099.33 ± 8.57

1082.33 ± 17.23

LYM

67.33 ± 2.96

64 ± 0.58

66.33 ± 1.2

62.67 ± 1.2

NEUT

28 ± 2.89

31 ± 1.53

29.67 ± 0.67

32.33 ± 1.2

MONO

3 ± 0.58

3 ± 0.58

2.33 ± 0.33

3 ± 0.58

EOS

1.67 ± 0.33

2 ± 0.58

1.67 ± 0.33

2 ± 0.58

  1. There was no significant difference in hematological parameters between nanoemulsion treated group and control group in male and female rats
  2. WBC (× 1000/mm3) White blood cells, RBC (× 1000/mm3) Red blood cells, HGB (g/dl) Hemoglobin, HCT (%) Hematocrits, MCV (fl) Mean corpuscular volume, MCH (pg) Mean corpuscular hemoglobin, MCHC (g/dl) Mean corpuscular hemoglobin concentration, PLT (× 1000/mm3) Platelets, LYM (%) Lymphocytes, NEUT (%) Neutrophils, MONO (%) Monocytes, EOS (%) Eosinophils