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Table 1 In vitro and in vivo antiplasmodial activity of crude extract of Terminalia albida stem bark from Dubréka (TaD) and Kankan (TaK), Guinea

From: Variation in chemical composition and antimalarial activities of two samples of Terminalia albida collected from separate sites in Guinea

 

In vitro IC50 (μg/mL)

% Parasite suppression (± SD)

against P. falciparum K1

against P. chabaudi

against P. berghei

Day 10

Day 5

Day 7

Day 8

CQ

0.09 ± 0.5

100

100

100

100

TaD

1.5 ± 0.4

56 ± 0.6

100

89 ± 0.3

61 ± 1.0

TaK

8.5 ± 1.2

14 ± 1.4

63 ± 0.7

35 ± 0.4

19 ± 1.27

  1. CQ chloroquine (5 mg/kg), TaD and TaK (100 mg/kg), SD standard deviation
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BMC Complementary Medicine and Therapies

ISSN: 2662-7671

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