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Table 1 In vitro and in vivo antiplasmodial activity of crude extract of Terminalia albida stem bark from Dubréka (TaD) and Kankan (TaK), Guinea

From: Variation in chemical composition and antimalarial activities of two samples of Terminalia albida collected from separate sites in Guinea

  In vitro IC50 (μg/mL) % Parasite suppression (± SD)
against P. falciparum K1 against P. chabaudi against P. berghei
Day 10 Day 5 Day 7 Day 8
CQ 0.09 ± 0.5 100 100 100 100
TaD 1.5 ± 0.4 56 ± 0.6 100 89 ± 0.3 61 ± 1.0
TaK 8.5 ± 1.2 14 ± 1.4 63 ± 0.7 35 ± 0.4 19 ± 1.27
  1. CQ chloroquine (5 mg/kg), TaD and TaK (100 mg/kg), SD standard deviation
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