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Table 4 Vasorelaxant effect of Otostegia integrifolia extract on rat thoracic aorta pre-contracted with 80 mM KCl

From: Methanol (80%) leaf extract of Otostegia integrifolia Benth (Lamiaceae) lowers blood pressure in rats through interference with calcium conductance

Concentration (μg/mL)

% Relaxation by the extract in KCl precontracted aorta

0.00

0.00 ± 0.00

6.25

1.25 ± 0.55

12.5

6.5 ± 1.98

25

21.0 ± 2.54***

50

44.5 ± 2.61***

100

76.3 ± 2.41***

125

100.00 ± 00***

  1. ***p < 0.001 (n = 10. Results are expressed as mean percentage contraction or relaxation ± SEM)