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Table 2 The effect of Otostegia integrifolia extract on systolic blood pressure in fructose induced hypertensive rat

From: Methanol (80%) leaf extract of Otostegia integrifolia Benth (Lamiaceae) lowers blood pressure in rats through interference with calcium conductance

Group Systolic BP
Day 0 Day 5 Day 10 Day 15
DF66 118.66 + 4.8 185.16 + 6.68 161 + 9.25 151.58 + 4.02
CAP20 108.41+ 2.45 98.66 + 4.81 b3c3d3e3 96.33 + 7.91 b3c1 93.00 + 5.31 b3
OI250 116.16+ 3.49 150.66 + 8.79 a2 135 + 13.17 109.75 + 11.64 a3
OI500 121.91+ 4.76 140 + 6.26 a3 87.08 + 9.24 a3 f2 109.33 + 3.08 a3
OI1000 110.25+ 6.13 142.41 + 3.17a3 96.91 + 4.51 a3 f1 102.91 + 4.17 a3
  1. Data are expressed as mean ± SEM (n = 6); Analysis was performed by one-way ANOVA; a, DF66 vs OI; b, DF66 vs CAP20; c, OI250 vs CAP20; d, OI500 vs CAP20; e, OI1000 vs CAP20; f, OI250 vs OI500 and OI100; DF66 Rats with 66% fructose ingestion, CAP20 Captopril 20 mg/kg, OI Otostegia integrifolia at doses of 250, 500 and 1000 mg/kg; 1p < 0.05; 2p < 0.01; 3p < 0.001.
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