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Table 1 Blood pressure changes after induction of hypertension with 66% w/v D-fructose in rats

From: Methanol (80%) leaf extract of Otostegia integrifolia Benth (Lamiaceae) lowers blood pressure in rats through interference with calcium conductance

BP Group BP Measurement Period
Day 0 Day 5 Day 10 Day 15
SBP NCR 112.75 +  3.99 109.50 +  4.31 101.16 + 7.2 111.41 + 0.96
DF66 118.66 +  4.8 185.16 +  6.68*** 161 + 9.25 *** 151.58 + 4.02***
DBP NCR 69.00 + 6.91 84.00 + 5.49 80.37 + 6.95 78.79 +  3.43
DF66 89.66 + 5.03 164.54 + 6.69*** 144.62 + 10.84*** 143.58 + 4.02***
MAP NCR 83.58 + 3.80 92.50 + 4.92 87.41 + 7.07 89.66 +  2.41
DF66 99.33 + 4.51 171.41 + 6.41*** 150.25 + 10.26*** 142.91 + 4.88***
NCR 43.75 + 10.12 16.87 +  2.64 33.62 + 5.2 22.00 + 1.95
PP DF66 25.50 + 3.05 14.00 + 4.11 18.32 + 1.52* 22.00 + 2.35
  1. Data are expressed as mean ± SEM (n = 6); Analysis was performed by one-way ANOVA; SBP Systolic blood pressure, DBP Diastolic blood pressure, MAP Mean arterial pressure, PP Pulse pressure, NCR Normal control rats without fructose ingestion, DF66 Rats with 66% fructose ingestion; *p < 0.05; ***p < 0.001.
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