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Table 4 Changes in SIBO results over time

From: Efficacy of a curcumin extract (Curcugen™) on gastrointestinal symptoms and intestinal microbiota in adults with self-reported digestive complaints: a randomised, double-blind, placebo-controlled study

  Baseline Week 8 Placebo Curcumin
Placebo (n = 39) Curcumin (n = 39) Difference *p-value Placebo (n = 34) Curcumin (n = 35) Difference *p-value #p-value #p-value
Hydrogen
 Elevated 51% 36% 15% .069 50% 46% 4% .447 .616 .124
 Borderline 18% 10% 8% 21% 11% 9%
 Negative 31% 54% −23% 29% 43% −13%
Methane
 Elevated 46% 33% 13% .395 44% 54% −10% .247 .670 .083
 Borderline 13% 21% −8% 15% 14% 0%
 Negative 41% 46% −5% 41% 31% 10%
Combined
 Elevated 72% 64% 8% .323 79% 74% 5% .420 .377 .794
 Borderline 21% 15% 5% 15% 3% 12%
 Negative 8% 21% −13% 6% 23% −17%
  1. * Mann-Whitney U-Test (between-group differences as time points); # Wilcoxon signed ranks test (within-group changes in SIBO results from baseline to week 8)