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Table 2 Changes in GSRS scores over time

From: Efficacy of a curcumin extract (Curcugen™) on gastrointestinal symptoms and intestinal microbiota in adults with self-reported digestive complaints: a randomised, double-blind, placebo-controlled study

    Baseline Week 4 Week 8 Repeated Measures ANOVA Cohen’s D effect size
p-value time effects p-value time x group interaction
GSRS: Total score Placebo (n = 39) Mean 2.65 2.00 2.18 <.001 .021 .57
SE 0.10 0.10 0.12
Curcumin (n = 38) Mean 2.91 2.24 2.10 <.001
SE 0.12 0.12 0.12
GSRS: Abdominal pain Placebo (n = 39) Mean 2.52 1.85 2.10 <.001 .124 .14
SE 0.14 0.12 0.15
Curcumin (n = 38) Mean 2.52 2.12 1.97 .001
SE 0.13 0.12 0.15
GSRS: Reflux Placebo (n = 39) Mean 2.04 1.81 1.88 .350 .638 .20
SE 0.18 0.17 0.20
Curcumin (n = 38) Mean 2.17 1.76 1.83 .021
SE 0.20 0.15 0.18
GSRS: Diarrhoea Placebo (n = 39) Mean 2.75 2.00 2.31 <.001 .314 .24
SE 0.24 0.16 0.21
Curcumin (n = 38) Mean 2.70 2.01 1.93 <.001
SE 0.24 0.18 0.18
GSRS: Indigestion Placebo (n = 39) Mean 3.18 2.22 2.46 <.001 .114 .41
SE 0.15 0.14 0.16
Curcumin (n = 38) Mean 3.53 2.52 2.39 <.001
SE 0.18 0.17 0.17
GSRS: Constipation Placebo (n = 39) Mean 2.43 1.98 1.97 .009 .160 .40
SE 0.20 0.14 0.16
Curcumin (n = 38) Mean 3.10 2.54 2.20 <.001
SE 0.26 0.22 0.20