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Table 3 Inhibition of EV-A71 viral infectivity by silymarin and baicalein from virucidal, cell protection and comprehensive assays

From: Antiviral activity of silymarin in comparison with baicalein against EV-A71

Compound (Concentration)

Quantification

Virucidal assay

Cell protection assay

Comprehensive assay

Silymarin (100 μg/mL)

Plaque assay

94.0%

16.6%

100.0%

qRT-PCR

84.3%

19.9%

97.0%

Baicalein (54 μg/mL)

Plaque assay

65.0%

2.2%

89.4%

qRT-PCR

78.8%

0.0%

83.0%

  1. The values presented indicated inhibitions of viral infectivity by silymarin (100 μg/mL) and baicalein (54 μg/mL) obtained from the virucidal, cell protection and comprehensive assays, respectively