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Table 1 Cytotoxicity of flavonoids against RD cells

From: Antiviral activity of silymarin in comparison with baicalein against EV-A71

Compound

CC50

CC10

Silymarin

160.20 ± 1.56 μg/mL

94.63 ± 2.29 μg/mL

Baicaleina

421.46 ± 3.23 μg/mL

90.93 ± 3.94 μg/mL

Baicalin

42.21 ± 4.15 μg/mL

5.46 ± 5.02 μg/mL

  1. Different concentrations of silymarin, baicalein and baicalin were tested for cytotoxicity in RD cells by the MTS assay. CC50 refers to half maximal cytotoxic concentration whereas CC10 is the toxic dose at 10%. Data are presented as mean ± standard error of the mean (S.E.M)
  2. aCC50 for baicalein is an extrapolated value as the value obtained is above the tested concentration of 108 μg/mL