Fig. 1

HS-Sultan/ADM, HS-Sultan /VCR, HS-Sultan /DEX, and HS-Sultan /L-PAM cell production and viability with various drugs. a HS-Sultan, HS-Sultan/ADM, HS-Sultan/VCR, HS-Sultan/DEX, and HS-Sultan/L-PAM cells were cultured with the represented concentrations of adriamycin, vincristine, dexamethasone, and melphalan. Cell number was appreciated using a trypan blue dye exclusion assay after 1, 3, 5, or 7 days. Results are notable example of five independent experiments. *p < 0.01 vs. untreated HS-Sultan cells (ANOVA with Dunnett’s test). b HS-Sultan, HS-Sultan/ADM, HS-Sultan/VCR, HS-Sultan/DEX, and HS-Sultan/L-PAM cells were cultured with the represented concentrations of adriamycin, vincristine, dexamethasone, and melphalan for 72 h. Cell viability was appreciated using a trypan blue dye exclusion assay. Results are notable example of five independent experiments. *p < 0.01 vs. control (ANOVA with Dunnett’s test). c Cross-resistance of drug-resistant BL cell lines. HS-Sultan/ADM, HS-Sultan/VCR, HS-Sultan/DEX, and HS-Sultan/L-PAM cells were cultured with 1 μM adriamycin, 10 nM vincristine, 20 μM dexamethasone, or 10 μM melphalan for 72 h. Cell number was detected using a trypan blue dye exclusion assay