Table 7 Blood pressure, renal functions, and liver functions in safety issue
Dataa | Treatment | Week 0 | Week 3 | Week 6 | p-value** |
|---|---|---|---|---|---|
Blood pressure | |||||
Systolic blood pressure | Ginger extract | 117.05 (9.60) | 113.76 (9.73) | 111.54 (17.91) | 0.767 |
(Normal ≤140 mm.Hg.) | Loratadine | 115.28 (13.16) | 114.37 (12.44) | 114.25 (14.86) | |
Diastolic blood pressure | Ginger extract | 75.95 (9.48) | 73.73 (9.99) | 74.58 (12.65) | 0.112 |
(Normal ≤90 mm.Hg.) | Loratadine | 72.10 (10.15) | 70.08 (11.74) | 71.19 (11.88) | |
Renal functions | 0.729 | ||||
Blood urea nitrogen; BUN (mg/dL) | Ginger extract | 11.81(3.47) | 11.26 (2.48) | 10.77 (3.32) | |
(ref. range = 7.0–18.0) | Loratadine | 11.50 (3.59) | 11.32 (2.71) | 10.61 (2.26) | |
Creatinine (mg/dL) | Ginger extract | 0.74 (0.18) | 0.76 (0.19) | 0.74 (0.23) | 0.826 |
(ref. range = 0.7–1.3) | Loratadine | 0.74 (0.18) | 0.75 (0.18) | 0.75 (0.16) | |
Liver functions | |||||
AST (U/L) (ref. range = 15–37) | Ginger extract | 21.13 (6.71) | 19.81 (5.18) | 20.19 (6.92) | 0.871 |
Loratadine | 20.85 (8.73) | 24.38 (14.66) | 20.56 (5.95) | ||
ALT (U/L) (ref. range = 30–65) | Ginger extract | 28.38 (11.96) | 27.51 (12.92) | 26.78 (11.39) | 0.586 |
Loratadine | 27.05 (13.35) | 29.51 (20.52) | 27.08 (12.28) | ||
ALP (U/L) (ref. range = 46–116) | Ginger extract | 60.93 (13.68) | 62.30 (16.73) | 58.11(17.66) | 0.118 |
Loratadine | 65.88 (21.93) | 67.89 (25.00) | 68.72 (25.04) | ||