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Table 2 Inhibition of the proliferation of U266 cells by the 10 chemical components

From: Frankincense and myrrh and their bioactive compounds ameliorate the multiple myeloma through regulation of metabolome profiling and JAK/STAT signaling pathway based on U266 cells

Componentsinhibition ratio (%)IC50(μmol/L)
10−4 M5 × 10−5 M2.5 × 10−5 M10− 5 M5 × 10−6 M
3-O-acetyl-boswellic acid84.18 ± 2.3859.22 ± 6.4144.06 ± 4.9611.65 ± 0.096.47 ± 2.1435.02
3α-acetyl-20 (29)-lupene-24-oic acid35.30 ± 0.4025.11 ± 2.7617.37 ± 0.8813.41 ± 1.887.54 ± 1.43293.20
β-boswellic acid43.68 ± 6.7522.99 ± 3.7920.18 ± 0.5716.48 ± 4.439.22 ± 0.44213.36
acetyl 11α-methoxy-β-boswellic acid47.66 ± 3.8435.18 ± 2.5431.52 ± 6.3830.32 ± 7.027.45 ± 0.95103.53
3α-acetoxy-tirucall-7,24-dien-21-oic acid18.90 ± 6.448.48 ± 1.665.62 ± 0.483.91 ± 0.791.76 ± 1.44665.81
3-acetyl-11-keto-β-boswellic acid68.58 ± 0.3539.13 ± 10.213.04 ± 1.427.42 ± 3.5610.14 ± 0.5267.79
11-keto-β-boswellic acid69.62 ± 1.569.05 ± 1.457.89 ± 10.912.64 ± 0.234.17 ± 10.4686.56
3-acetyl-β-boswellic acid34.27 ± 6.9526.34 ± 2.6516.98 ± 6.9714.24 ± 1.845.39 ± 0.81267.88
abietic acid24.37 ± 5.4118.25 ± 4.0313.70 ± 2.607.52 ± 1.275.11 ± 2.39643.48
2-methoxy-8,11-epoxygermacra-1 (10)-7,11-trien-6-one27.17 ± 3.7223.42 ± 3.6822.74 ± 3.7115.02 ± 0.9111.09 ± 4.711411.47