Skip to main content

Table 2 Inhibition of the proliferation of U266 cells by the 10 chemical components

From: Frankincense and myrrh and their bioactive compounds ameliorate the multiple myeloma through regulation of metabolome profiling and JAK/STAT signaling pathway based on U266 cells

Components

inhibition ratio (%)

IC50(μmol/L)

10−4 M

5 × 10−5 M

2.5 × 10−5 M

10− 5 M

5 × 10−6 M

3-O-acetyl-boswellic acid

84.18 ± 2.38

59.22 ± 6.41

44.06 ± 4.96

11.65 ± 0.09

6.47 ± 2.14

35.02

3α-acetyl-20 (29)-lupene-24-oic acid

35.30 ± 0.40

25.11 ± 2.76

17.37 ± 0.88

13.41 ± 1.88

7.54 ± 1.43

293.20

β-boswellic acid

43.68 ± 6.75

22.99 ± 3.79

20.18 ± 0.57

16.48 ± 4.43

9.22 ± 0.44

213.36

acetyl 11α-methoxy-β-boswellic acid

47.66 ± 3.84

35.18 ± 2.54

31.52 ± 6.38

30.32 ± 7.02

7.45 ± 0.95

103.53

3α-acetoxy-tirucall-7,24-dien-21-oic acid

18.90 ± 6.44

8.48 ± 1.66

5.62 ± 0.48

3.91 ± 0.79

1.76 ± 1.44

665.81

3-acetyl-11-keto-β-boswellic acid

68.58 ± 0.35

39.13 ± 10.2

13.04 ± 1.42

7.42 ± 3.56

10.14 ± 0.52

67.79

11-keto-β-boswellic acid

69.62 ± 1.56

9.05 ± 1.45

7.89 ± 10.91

2.64 ± 0.23

4.17 ± 10.46

86.56

3-acetyl-β-boswellic acid

34.27 ± 6.95

26.34 ± 2.65

16.98 ± 6.97

14.24 ± 1.84

5.39 ± 0.81

267.88

abietic acid

24.37 ± 5.41

18.25 ± 4.03

13.70 ± 2.60

7.52 ± 1.27

5.11 ± 2.39

643.48

2-methoxy-8,11-epoxygermacra-1 (10)-7,11-trien-6-one

27.17 ± 3.72

23.42 ± 3.68

22.74 ± 3.71

15.02 ± 0.91

11.09 ± 4.71

1411.47