Fig. 9

Effects of SSB extract on liver Hedgehog, Ptch, Smo, Gli, P13k, and Akt protein and gene expression levels in mice with LPS/D-GalN-induced acute liver injury. a–b Representative RT-PCR showing Hedgehog, Ptch, Smo, Gli, P13k, and Akt gene expression levels in liver tissue 24 h after the administration of LPS/D-GalN plus SSB extract. c–d Representative Western blot analysis showing Hedgehog, Ptch, Smo, Gli, P13k, and Akt protein expression levels in liver tissue 24 h after the administration of LPS/D-GalN plus SSB extract. e Statistical summary of densitometric analysis of Hedgehog, Ptch, Smo, Gli, P13k, and Akt protein expression in mouse liver tissue 24 h after the administration of LPS/D-GalN plus SSB extract. Data are expressed as mean ± SD. **P < 0.01: compared with the control group; #P < 0.05 and ##P < 0.01: compared with the model group. P > 0.05: control group compared with the control treatment group